Recent advances in nanotherapeutic strategies for spinal cord injury repair
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چکیده
منابع مشابه
recent advances in cell therapy of spinal cord injury
abstract spinal cord injury (sci) is a devastating condition producing great personal and societal costs and for which there is no effective treatment. stem cell transplantation is a promising therapeutic strategy, though much preclinical and clinical research work remains. here, we briefly describe sci epidemiology, pathophysiology, and transplantation trial in human developments, including te...
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specialized courses and in the broader context of general biology education. It is published four times a year in is dedicated to the improvement of teaching and learning physiology, both in Advances in Physiology Education
متن کاملRecent advances in pathophysiology and treatment of spinal cord injury.
Thirty years ago, patients with spinal cord injury (SCI) and their families were told "nothing can be done" to improve function. Since the SCI patient population is reaching normal life expectancy through better health care, it has become an obviously worthwhile enterprise to devote considerable research effort to SCI. Targets for intervention in SCI toward improved function have been identifie...
متن کاملRepair and neurorehabilitation strategies for spinal cord injury.
The failure of axons in the central nervous system (CNS) to regenerate has been considered the main factor limiting recovery from spinal cord injury (SCI). Impressive gains in identification of growth-inhibitory molecules in the CNS led to expectations that their neutralization would lead to functional regeneration. However, results of therapeutic approaches based on this assumption have been m...
متن کاملBioengineered strategies for spinal cord repair.
This article reviews bioengineered strategies for spinal cord repair using tissue engineered scaffolds and drug delivery systems. The pathophysiology of spinal cord injury (SCI) is multifactorial and multiphasic, and therefore, it is likely that effective treatments will require combinations of strategies such as neuroprotection to counteract secondary injury, provision of scaffolds to replace ...
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ژورنال
عنوان ژورنال: Advanced Drug Delivery Reviews
سال: 2019
ISSN: 0169-409X
DOI: 10.1016/j.addr.2018.12.011